Document Detail

The emergence of severe, community-acquired methicillin-resistant Staphylococcus aureus infections.
MedLine Citation:
PMID:  16126565     Owner:  NLM     Status:  MEDLINE    
The number of community acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections is rapidly increasing. Most CA-MRSA infections are localized soft tissue infections; however, severe life-threatening infections have been occasionally described. This report serves to increase the awareness of severe CA-MRSA infections by presenting a fulminant CA-MRSA infection with sepsis, endocarditis, septic pulmonary emboli, and extensive soft tissue and bone destruction. A review of the literature revealed 14 cases of severe CA-MRSA infections with a median age of 13 y; 93% had no underlying medical condition. Only 1 case was initially treated with antibiotics effective for MRSA. The fatality rate was 64%, and 40% of patients who survived had significant disabilities.
Nancy F Crum
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Scandinavian journal of infectious diseases     Volume:  37     ISSN:  0036-5548     ISO Abbreviation:  Scand. J. Infect. Dis.     Publication Date:  2005  
Date Detail:
Created Date:  2005-08-29     Completed Date:  2005-11-01     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0215333     Medline TA:  Scand J Infect Dis     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  651-6     Citation Subset:  IM    
Infectious Diseases Division, Naval Medical Center San Diego, San Diego, CA 92134, USA.
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MeSH Terms
Community-Acquired Infections / diagnosis,  microbiology,  physiopathology
Methicillin Resistance*
Severity of Illness Index
Staphylococcal Infections / diagnosis,  microbiology*,  physiopathology
Staphylococcus aureus / drug effects*,  isolation & purification

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