Document Detail

The emergence of case-control studies in hypertension research: valid or misleading?
MedLine Citation:
PMID:  9263664     Owner:  NLM     Status:  MEDLINE    
Recently published case-control studies have generated considerable controversy. Compared with prospective studies, case-control studies permit investigation of uncommon diseases or outcomes in a more cost and time efficient manner. In addition, multiple possible risk factors can be studied simultaneously. If the assumptions of the study design are met, results of case-control studies are valid. For this reason, the use of this study design has increased markedly. This review summarizes the advantages and disadvantages of this study design and criteria to evaluate the results of such studies.
J C Longenecker; M J Klag
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  Current opinion in nephrology and hypertension     Volume:  6     ISSN:  1062-4821     ISO Abbreviation:  Curr. Opin. Nephrol. Hypertens.     Publication Date:  1997 May 
Date Detail:
Created Date:  1997-09-29     Completed Date:  1997-09-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9303753     Medline TA:  Curr Opin Nephrol Hypertens     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  224-9     Citation Subset:  IM    
Johns Hopkins University School of Medicine, Division of General Internal Medicine, Welch Center for Prevention, Epidemiology and Clinical Research, Baltimore, Maryland 21205-2223, USA.
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MeSH Terms
Calcium Channel Blockers / adverse effects
Case-Control Studies
Clinical Protocols
Hypertension* / drug therapy
Myocardial Infarction / etiology
Odds Ratio
Prospective Studies
Research Design
Reg. No./Substance:
0/Calcium Channel Blockers

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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