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<em>In Vitro</em> Antioxidant Properties of Flavonoids and Polysaccharides Extract from Tobacco (<em>Nicotiana</em><em> </em><em>tabacum</em> L.) Leaves.
MedLine Citation:
PMID:  23001388     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
In the present study, antioxidant properties of flavonoids and polysaccharides from tobacco (<em>Nicotiana</em><em> tabacum</em> L.) leaves were evaluated in several <em>in vitro</em> systems, e.g., scavenging activities on hydroxyl, superoxide anion, 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) radicals, and reducing power. Flavonoids showed much better activity than polysaccharides in scavenging activities on free radicals. When compared to the positive control, ascorbic acid, both showed weaker antioxidant potential. However, flavonoids possessed comparable superoxide anion, DPPH and ABTS radical scavenging abilities to ascorbic acid at high concentration (600 μg/mL). Meanwhile, it was found that flavonoids had prominent effects on the reducing power, which was equivalent to ascorbic acid, and was significantly higher than polysaccharides. These results clearly indicate that flavonoids are effective in scavenging free radicals and have the potential to be powerful antioxidants. Thus, tobacco leaves could be considered as a potential source of natural antioxidants for food, pharmaceutical, cosmetics or nutraceutical industries.
Authors:
Qiao-Mei Ru; Li-Juan Wang; Wei-Ming Li; Jing-Lu Wang; Yu-Ting Ding
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Publication Detail:
Type:  Journal Article     Date:  2012-09-21
Journal Detail:
Title:  Molecules (Basel, Switzerland)     Volume:  17     ISSN:  1420-3049     ISO Abbreviation:  Molecules     Publication Date:  2012  
Date Detail:
Created Date:  2012-09-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100964009     Medline TA:  Molecules     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  11281-91     Citation Subset:  IM    
Affiliation:
College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China. dingyt@zjut.edu.cn.
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