| An electroimmuno-assay of the pregnancy-specific beta1-glycoprotein (SP1) in normal and pathological pregnancies, and its clinical value compared to human chorionic somato-mammotropin (HCS). | |
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MedLine Citation:
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PMID: 566505 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 95% reference interval for the pregnancy-specific beta1-glycoprotein (SP1) was established on the basis of 299 samples from 254 normal pregnant women by electroimmuno-assay (rocket immunoelectrophoresis). A positive correlation was found between SP1 and the human chorionic somato-mammotropin (HCS). The SP1 concentration in maternal blood was halved about 30 hours after separation of the placenta at delivery. Thus emergency analyses would be of little value in detecting acute placentae failure. 172 determinations of SP1 in maternal sera were carried out on 56 pregnant women with various types of pathological pregnancies. To assess the clinical value of SP1 a comparison with HCS (HPL) was made. It was concluded that SP1 could possibly be a valuable parameter for monitoring and discovering pathological pregnancies. Larger investigations, however, must be performed to decide whether SP1 determinations will provide more extensive information than other laboratory analyses presently used. |
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Authors:
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S Sørensen |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Acta obstetricia et gynecologica Scandinavica Volume: 57 ISSN: 0001-6349 ISO Abbreviation: Acta Obstet Gynecol Scand Publication Date: 1978 |
Date Detail:
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Created Date: 1978-08-14 Completed Date: 1978-08-14 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370343 Medline TA: Acta Obstet Gynecol Scand Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 193-201 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Asphyxia Neonatorum Evaluation Studies as Topic Female Fetal Death / blood Glycoproteins / blood* Humans Hypertension / blood Immunoelectrophoresis Infant, Newborn Infant, Premature Organ Size Parity Placenta Placenta Diseases / diagnosis* Placenta Previa / diagnosis Placental Lactogen / blood* Pregnancy* Pregnancy Complications / diagnosis* Twins |
| Chemical | |
Reg. No./Substance:
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0/Glycoproteins; 9035-54-5/Placental Lactogen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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