Document Detail

An electrochemical sensor for phenylephrine based on molecular imprinting.
MedLine Citation:
PMID:  19745535     Owner:  NLM     Status:  MEDLINE    
Molecularly imprinted polymers (MIPs) were applied as molecular recognition elements to an electrochemical sensor for phenylephrine. A MIPs membrane was created on a glassy carbon electrode. SEM revealed a gradual change on the morphology of modified electrodes as the ratios of function monomer and cross-linking varied. When the ratio was 4:40, the surface morphology between the imprinted electrode (M-electrode) and the control electrode (N-electrode) became unambiguously different. This artificial receptor exhibited high selectivity for the template compared to closely related analogue. The response of the sensor varied in different concentration range might due to the heterogeneity of the MIPs membrane. This sensor was also used to determine phenylephrine in tablet samples.
Liuduan Yao; Youwen Tang; Weipeng Zeng; Zhaofa Huang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry     Volume:  25     ISSN:  1348-2246     ISO Abbreviation:  Anal Sci     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-09-11     Completed Date:  2009-12-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8511078     Medline TA:  Anal Sci     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1089-93     Citation Subset:  IM    
Department of Chemistry, South China Normal University, Guangzhou 510006, China.
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MeSH Terms
Carbon / chemistry
Chemistry, Analytic / economics,  instrumentation*
Glass / chemistry
Membranes, Artificial
Molecular Imprinting
Phenylephrine / analysis*,  chemistry
Polymers / chemistry
Surface Properties
Tablets / chemistry
Time Factors
Reg. No./Substance:
0/Membranes, Artificial; 0/Polymers; 0/Tablets; 59-42-7/Phenylephrine; 7440-44-0/Carbon

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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