Document Detail

An electrocardiogram-based method for early detection of abrupt changes in blood pressure during hemodialysis.
MedLine Citation:
PMID:  16760717     Owner:  NLM     Status:  MEDLINE    
Clinical techniques for early detection of acute hypotension during conventional hemodialysis treatment are lacking, even though intradialytic hypotension is the most common acute complication. In this article, intradialytic hypotension is identified by means of signal analysis of data recorded at two clinics. The database consists of 30 treatments with concurrently acquired signals: the 12-lead electrocardiogram, continuous blood pressure, hematocrit, oxygen saturation, relative blood volume, and important hemodialysis variables. This article presents two characteristics, a heart rate turbulence (HRT) measure called turbulence slope (TS), and the LF/HF ratio, which provide information, at the beginning of hemodialysis treatment, on the patient's propensity to hypotension (TS: p = 0.0038, and LF/HF ratio: p = 0.0028). The authors also present a novel dynamic echocardiography-based method for detecting intradialytic hypotension using complementary information on heart rate variability (HRV) and ectopic beat patterns. These two types of information reflect different mechanisms of cardiac activity. It is essential that both types are used for the detection of hypotension, because HRV analysis is inappropriate when several ectopic beats are present. The proposed dynamic echocardiography-based method offers early identification of the cases with acute intradialytic hypotension of the database.
Kristian Solem; Anders Nilsson; Leif Sörnmo
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  ASAIO journal (American Society for Artificial Internal Organs : 1992)     Volume:  52     ISSN:  1058-2916     ISO Abbreviation:  ASAIO J.     Publication Date:    2006 May-Jun
Date Detail:
Created Date:  2006-06-08     Completed Date:  2006-08-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9204109     Medline TA:  ASAIO J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  282-90     Citation Subset:  IM    
Signal Processing Group, Department of Electroscience, Lund University, Lund, Sweden.
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MeSH Terms
Blood Pressure
Heart Rate
Hypotension* / diagnosis,  etiology,  physiopathology
Middle Aged
Renal Dialysis / adverse effects*
Signal Processing, Computer-Assisted

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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