Document Detail

An elderly case of moyamoya disease presenting with hemichorea.
MedLine Citation:
PMID:  22260975     Owner:  NLM     Status:  In-Data-Review    
A 61-year-old Japanese female was admitted with sudden onset of choreic movements of the right extremities. MRI demonstrated no abnormality suggestive of acute infarcts. Cerebral angiography revealed high-grade stenosis of bilateral middle cerebral arteries at the origin and abnormal vascular network compatible with moyamoya disease. Administration of low-dose haloperidol rapidly resolved the choreic movements. SPECT obtained one month after the clinical onset demonstrated increase of the regional cerebral blood flow (rCBF) in the left basal ganglia. Moyamoya disease presenting chorea as its initial symptom was only infrequently reported in the elderly. In the present case, increased rCBF in the basal ganglia and remarkable effect of a dopamine D2 blocker suggest functional abnormality of the corresponding striatum as an underlying cause of hemichorea.
Masato Kinboshi; Manabu Inoue; Yasuhiro Kojima; Tomokazu Nakagawa; Masutaro Kanda; Hiroshi Shibasaki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Rinshō shinkeigaku = Clinical neurology     Volume:  52     ISSN:  0009-918X     ISO Abbreviation:  Rinsho Shinkeigaku     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-01-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0417466     Medline TA:  Rinsho Shinkeigaku     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  25-9     Citation Subset:  IM    
Department of Neurology, Ijinkai Takeda General Hospital.
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