Document Detail

The efficiency of a weighed log-rank test under a percent error misspecification model for the log hazard ratio.
MedLine Citation:
PMID:  1420846     Owner:  NLM     Status:  MEDLINE    
For comparison of two survival distributions, it is natural to use a weighted log-rank test with weight function given by the log hazard ratio function that is anticipated a priori. This paper investigates the efficiency of this test when the a priori estimate of the log hazard ratio is subject to a specified percentage error. The test is shown to be the maximum efficiency robust test over the class of alternatives in question and a simple expression for the maximum efficiency is established.
D M Zucker
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Biometrics     Volume:  48     ISSN:  0006-341X     ISO Abbreviation:  Biometrics     Publication Date:  1992 Sep 
Date Detail:
Created Date:  1992-12-02     Completed Date:  1992-12-02     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370625     Medline TA:  Biometrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  893-9     Citation Subset:  IM    
Biostatistics Research Branch, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20892.
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MeSH Terms
Clinical Trials as Topic / methods*
Proportional Hazards Models*
Survival Analysis*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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