Document Detail

The efficacy of systematic active conservative treatment for patients with severe sciatica: a single-blind, randomized, clinical, controlled trial.
MedLine Citation:
PMID:  21494193     Owner:  NLM     Status:  MEDLINE    
STUDY DESIGN: Prospective single-blind, randomized, clinical, controlled trial.
OBJECTIVE: To evaluate the efficacy of active conservative treatment and to compare 2 active conservative treatment programs for patients with severe sciatica.
SUMMARY OF BACKGROUND DATA: Reviews have demonstrated little or no efficacy for passive conservative treatment modalities in patients suffering from sciatica. The results for surgery are conflicting. Cohort studies have shown excellent results for active treatment modalities in patients with sciatica.
METHODS: One hundred eighty-one consecutive patients with radicular pain below the knee were examined at the baseline, at 8 weeks, and at 1 year after the treatment. Participants were randomized into 2 groups: (1) symptom-guided exercises + information + advice to stay active and (2) sham exercises + information + advice to stay active. Symptom-guided exercises consisted of a variety of back-related exercises given in accordance with a written algorithm in which symptoms or response to exercises determined the exercises given (, click exercises). Sham exercises were optional, designed to increase general blood circulation, and had no targeted effect on the back. The information was comprehensive and included anatomy, pathogenesis, and how discs heal without surgery. The advice included encouragement to stay as active as possible but to reduce activity if leg pain increased. The use of medication was optional, but only paracetamol and nonsteroidal anti-inflammatory drugs were recommended.
RESULTS: A mean of 4.8 treatment sessions were provided. All patients experienced statistically significant and clinically important improvements in global assessment, functional status, pain, vocational status, and clinical findings. The symptom-guided exercise group improved significantly more than the sham exercise group in most outcomes.
CONCLUSION: Active conservative treatment was effective for patients who had symptoms and clinical findings that would normally qualify them for surgery. Although participating patients had greater faith in the sham exercises before treatment, the symptom-guided exercises were superior for most outcomes.
Hanne B Albert; Claus Manniche
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Spine     Volume:  37     ISSN:  1528-1159     ISO Abbreviation:  Spine     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-03-30     Completed Date:  2012-07-25     Revised Date:  2013-04-29    
Medline Journal Info:
Nlm Unique ID:  7610646     Medline TA:  Spine (Phila Pa 1976)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  531-42     Citation Subset:  IM    
Back Research Centre, Funen, University of Southern Denmark, Ringe, Denmark.
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MeSH Terms
Exercise Therapy / methods*
Low Back Pain / therapy*
Middle Aged
Prospective Studies
Sciatica / therapy*
Single-Blind Method
Treatment Outcome
Comment In:
Evid Based Med. 2013 Apr;18(2):63-4   [PMID:  22893657 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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