Document Detail

The efficacy and safety of epidural infusions of levobupivacaine with and without clonidine for postoperative pain relief in patients undergoing total hip replacement.
MedLine Citation:
PMID:  10910855     Owner:  NLM     Status:  MEDLINE    
IMPLICATIONS: In patients undergoing total hip replacement, the addition of the alpha(2)-adrenergic agonist clonidine to epidural infusions of levobupivacaine significantly improved postoperative analgesia.
K R Milligan; P N Convery; P Weir; P Quinn; D Connolly
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  91     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  2000 Aug 
Date Detail:
Created Date:  2000-08-15     Completed Date:  2000-08-15     Revised Date:  2014-07-28    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  393-7     Citation Subset:  AIM; IM    
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MeSH Terms
Analgesia, Epidural*
Analgesics / administration & dosage*
Analgesics, Opioid / therapeutic use
Anesthetics, Local / administration & dosage*
Arthroplasty, Replacement, Hip*
Bupivacaine / administration & dosage*
Clonidine / administration & dosage*
Morphine / therapeutic use
Pain Measurement
Pain, Postoperative / drug therapy,  prevention & control*
Reg. No./Substance:
0/Analgesics; 0/Analgesics, Opioid; 0/Anesthetics, Local; 76I7G6D29C/Morphine; MN3L5RMN02/Clonidine; Y8335394RO/Bupivacaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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