Document Detail

The efficacy of multiple-dose methotrexate treatment for unruptured tubal ectopic pregnancy and conversion rate to surgery: a study on 294 cases.
MedLine Citation:
PMID:  20137786     Owner:  NLM     Status:  MEDLINE    
In this prospective study 294 patients diagnosed with ectopic pregnancy (EP) were treated with multiple-dose methotrexate (MTX) to determine the conversion rate to surgery. We concluded that multiple-dose MTX treatment had a low success rate, and the success rate was not related to initial b-hCG value; it was more related to the size of gestational mass before treatment.
Osman Balci; Suna Ozdemir; Alaa S Mahmoud; Ali Acar; Mehmet C Colakoglu
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Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2010-02-04
Journal Detail:
Title:  Fertility and sterility     Volume:  93     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-26     Completed Date:  2010-05-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2415-7     Citation Subset:  IM    
Copyright Information:
Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Department of Obstetrics and Gynecology, Meram Medicine Faculty, Selcuk University, Akyokus, 42080, Konya, Turkey.
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MeSH Terms
Abortifacient Agents, Nonsteroidal / administration & dosage
Dose-Response Relationship, Drug
Drug Administration Schedule
Embryo, Mammalian / pathology
Fallopian Tubes / drug effects,  pathology
Follow-Up Studies
Gestational Age
Gynecologic Surgical Procedures / statistics & numerical data*
Injections, Intramuscular
Methotrexate / administration & dosage*
Organ Size
Pregnancy, Ectopic / drug therapy*,  epidemiology,  pathology,  surgery*
Treatment Failure
Treatment Outcome
Reg. No./Substance:
0/Abortifacient Agents, Nonsteroidal; 59-05-2/Methotrexate

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