| The efficacy of lidocaine administered via the LITA tracheal tube in attenuating the extubation response in beta-blocked patients following craniotomy. | |
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MedLine Citation:
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PMID: 11949645 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The Laryngotracheal Instillation of Topical Anaesthetic (LITA) tracheal tube has an additional pilot tube through which local anaesthetic can be instilled into the larynx via 10 small holes above and below the cuff We studied 40 patients undergoing supratentorial craniotomy. They were premedicated with two oral doses of propranolol 1 mg.kg(-1). The anaesthetic consisted of infusions of remifentanil, propofol and vecuronium. On insertion of the first skin clip at the end of surgery, 5 ml of either saline or 2% lidocaine was injected into the appropriate lumen of the tracheal tube. There was no difference between the groups in the degree of coughing or the haemodynamic response to tracheal extubation. |
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Authors:
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J Andrzejowski; G Francis |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Anaesthesia Volume: 57 ISSN: 0003-2409 ISO Abbreviation: Anaesthesia Publication Date: 2002 Apr |
Date Detail:
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Created Date: 2002-04-11 Completed Date: 2002-05-01 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370524 Medline TA: Anaesthesia Country: England |
Other Details:
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Languages: eng Pagination: 399-401 Citation Subset: AIM; IM |
Affiliation:
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Department of Anaesthesia, Royal Hallamshire Hospital, Sheffield, UK. John.Andrzejowski@sth.nhs.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adrenergic beta-Antagonists / pharmacology Adult Aged Aged, 80 and over Anesthetics, Local / pharmacology* Cough / prevention & control Craniotomy* Device Removal / adverse effects Female Hemodynamics / drug effects* Humans Intubation, Intratracheal* / instrumentation Lidocaine / pharmacology* Male Middle Aged Postoperative Complications / prevention & control |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 0/Anesthetics, Local; 137-58-6/Lidocaine |
| Comments/Corrections | |
Comment In:
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Anaesthesia. 2002 Oct;57(10):1034-5; author reply 1035
[PMID:
12358971
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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