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The efficacy of irvingia gabonensis supplementation in the management of overweight and obesity: a systematic review of randomized controlled trials.
MedLine Citation:
PMID:  23419021     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
ABSTRACT The aim of this systematic review was to evaluate the evidence from randomized controlled trials (RCTs) involving the use of the African Bush Mango, Irvingia gabonensis for body weight reduction in obese and overweight individuals. Electronic and nonelectronic searches were conducted to identify relevant RCTs. The bibliographies of located articles were also searched. No age, gender, or language restrictions were imposed. The reporting quality of identified RCTs was assessed using a methodological checklist adapted from the Consolidated Standard of Reporting Trials Statement and Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. Two reviewers independently determined eligibility and assessed the reporting quality of included studies. Three RCTs were identified, and all were included. The RCTs all had flaws in the reporting of their methodology. All RCTs reported statistically significant reductions in body weight and waist circumference favoring I. gabonensis over placebo. The results from the RCTs also suggest positive effects of I. gabonensis supplementation on the blood lipid profile. Adverse events included headache and sleep difficulty. Due to the paucity and poor reporting quality of the RCTs, the effect of I. gabonensis on body weight and related parameters are unproven. Therefore, I. gabonensis cannot be recommended as a weight loss aid. Future research in this area should be more rigorous and better reported.
Authors:
Igho Onakpoya; Lucy Davies; Paul Posadzki; Edzard Ernst
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of dietary supplements     Volume:  10     ISSN:  1939-022X     ISO Abbreviation:  J Diet Suppl     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101249830     Medline TA:  J Diet Suppl     Country:  England    
Other Details:
Languages:  eng     Pagination:  29-38     Citation Subset:  IM    
Affiliation:
Complementary Medicine, Peninsula Medical School , University of Exeter , United Kingdom.
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