Document Detail

The efficacy of ginger for the prevention of postoperative nausea and vomiting: a meta-analysis.
MedLine Citation:
PMID:  16389016     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The aim of this study was to specifically determine the impact of a fixed dose of ginger administration, compared with placebo, on the 24-hour postoperative nausea and vomiting. STUDY DESIGN: The design was a systematic review and metaanalysis of trials revealed by searches. Randomized controlled trials comparing ginger with placebo to prevent postoperative nausea and vomiting and postoperative vomiting from Medline, IPA, CINAHL, Cochrane CENTRAL, HealthStar, Current Contents, bibliographies of retrieved articles, contact of authors, and experts in the field. Two reviewers selected studies for inclusion and independently extracted data. RESULTS: Five randomized trials including a total of 363 patients were pooled for analysis of preventing postoperative nausea and vomiting and postoperative vomiting. The summary relative risks of ginger for postoperative nausea and vomiting and postoperative vomiting were 0.69 (95% confidence interval 0.54 to 0.89) and 0.61 (95% confidence interval 0.45 to 0.84), respectively. Only one side effect, abdominal discomfort, was reported. CONCLUSIONS: This meta-analysis demonstrates that a fixed dose at least 1 g of ginger is more effective than placebo for the prevention of postoperative nausea and vomiting and postoperative vomiting. Use of ginger is an effective means for reducing postoperative nausea and vomiting.
Nathorn Chaiyakunapruk; Nantawarn Kitikannakorn; Surakit Nathisuwan; Kittiboon Leeprakobboon; Chutchai Leelasettagool
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Publication Detail:
Type:  Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  194     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-01-03     Completed Date:  2006-04-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  95-9     Citation Subset:  AIM; IM    
Department of Pharmacy Practice, School of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand.
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MeSH Terms
Ginger* / adverse effects
Postoperative Nausea and Vomiting / etiology,  prevention & control*
Randomized Controlled Trials as Topic
Treatment Outcome
Comment In:
Evid Based Nurs. 2006 Jul;9(3):80   [PMID:  16865831 ]

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