Document Detail

The efficacy of the disinfection of bronchoscopes contaminated in vitro with Mycobacterium tuberculosis and Mycobacterium avium-intracellulare in sputum: a comparison of Sactimed-I-Sinald and glutaraldehyde.
MedLine Citation:
PMID:  7658005     Owner:  NLM     Status:  MEDLINE    
The efficacy of Sactimed-I-Sinald and glutaraldehyde was tested against clinical isolates of Mycobacterium tuberculosis (MTB) and Mycobacterium avium-intracellulare (MAI). An in-use method demonstrated that over 10 disinfection cycles, using an auto-disinfector and a contact time of 60 min, MTB was eradicated in 10 out of 10 cycles with Sactimed-I-Sinald and five out of 10 cycles for glutaraldehyde. For MAI, Sactimed-I-Sinald showed a 5 log reduction at a 60 min contact time, which was not seen with glutaraldehyde. Although further evaluation is necessary, Sactimed-I-Sinald appears a promising alternative to glutaraldehyde.
G Nicholson; R A Hudson; M V Chadwick; H Gaya
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Journal of hospital infection     Volume:  29     ISSN:  0195-6701     ISO Abbreviation:  J. Hosp. Infect.     Publication Date:  1995 Apr 
Date Detail:
Created Date:  1995-10-04     Completed Date:  1995-10-04     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8007166     Medline TA:  J Hosp Infect     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  257-64     Citation Subset:  IM    
Department of Microbiology, Royal Brompton Hospital, London, UK.
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MeSH Terms
Disinfectants / pharmacology
Disinfection / methods*
Equipment Contamination / prevention & control*
Evaluation Studies as Topic
Glutaral / pharmacology
Guanidines / pharmacology
Mycobacterium avium Complex / drug effects*,  isolation & purification
Mycobacterium tuberculosis / drug effects*,  isolation & purification
Quaternary Ammonium Compounds / pharmacology
Sputum / microbiology
Reg. No./Substance:
0/Disinfectants; 0/Guanidines; 0/Quaternary Ammonium Compounds; 0/Sactimed-I-Sinald; 111-30-8/Glutaral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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