Document Detail


The efficacy of bromides, stiripentol and levetiracetam in two patients with malignant migrating partial seizures in infancy.
MedLine Citation:
PMID:  21393091     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The syndrome of malignant migrating partial seizures in infancy is a devastating, age-specific, epileptic encephalopathy, which still presents an aetiological, pathophysiological and therapeutic problem. In this study, we present two patients who were diagnosed with the disease, based on electroclinical symptoms. The patients were treated with a combination of sodium bromide, stiripentol and levetiracetam. The first patient unequivocally responded, following a course of ineffective conventional drugs, and the second, who was diagnosed and treated immediately, showed a more significant therapeutic response. Antiepileptic drugs, previously reported to be beneficial in case reports, when given concomitantly, may substantially reduce the number and severity of seizures, without influence on psychomotor development. <i>[Published with video sequences]</i>
Authors:
Milena Djuric; Ruzica Kravljanac; Gordana Kovacevic; Jelena Martic
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-10
Journal Detail:
Title:  Epileptic disorders : international epilepsy journal with videotape     Volume:  -     ISSN:  1294-9361     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100891853     Medline TA:  Epileptic Disord     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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