Document Detail


The effects of yellow soybean, black soybean, and sword bean on lipid levels and oxidative stress in ovariectomized rats.
MedLine Citation:
PMID:  20803424     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Soy isoflavones have been reported to decrease the risk of atherosclerosis in postmenopausal women. However, the effects of dietary consumption of soybean have not been explored. In this study, we evaluated the effects of consuming yellow soybeans, black soybeans (Glycine max), or sword beans (Canavalia gladiate) on lipid and oxidative stress levels in an ovariectomized rat model. Forty-seven nine-week-old female rats were ovariectomized, randomly divided into four groups, and fed one of the following diets for 10 weeks: a diet supplemented with casein (NC, n = 12), a diet supplemented with yellow soybean (YS, n = 12), a diet supplemented with black soybean (BS, n = 12), or a diet supplemented with sword bean (SB, n = 11). Plasma triglyceride (TG) levels in the BS and SB groups were significantly lower than that in the NC group. Notably, the BS group had significantly lower plasma total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C) levels than the other groups. Hepatic total lipid levels were significantly lower in the YS and SB groups, and cholesterol levels were significantly lower in the SB group than in the NC group. Superoxide dismutase (SOD) and catalase (CAT) activities were significantly higher in the groups fed beans compared to the NC group. Hepatic thiobarbituric acid reactive substances (TBARS) levels were also significantly lower in the BS and SB groups than the NC group. In conclusion, our results suggest that consumption of various types of beans may inhibit oxidative stress in postmenopausal women by increasing antioxidant activity and improving lipid profiles. Notably, intake of black soybean resulted in the greatest improvement in risk factors associated with cardiovascular disease.
Authors:
Jae Soon Byun; Young Sun Han; Sang Sun Lee
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition     Volume:  80     ISSN:  0300-9831     ISO Abbreviation:  Int J Vitam Nutr Res     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-08-30     Completed Date:  2010-10-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1273304     Medline TA:  Int J Vitam Nutr Res     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  97-106     Citation Subset:  IM    
Affiliation:
Department of Food & Nutrition, Hanyang University, Seoul, South Korea.
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MeSH Terms
Descriptor/Qualifier:
Analysis of Variance
Animals
Biological Markers / metabolism
Canavalia*
Caseins / administration & dosage
Catalase / metabolism
Cholesterol / blood
Diet / methods
Disease Models, Animal
Female
Lipid Metabolism*
Lipids / blood*
Liver / metabolism
Ovariectomy
Oxidative Stress*
Rats
Rats, Sprague-Dawley
Soybeans*
Superoxide Dismutase / metabolism
Thiobarbituric Acid Reactive Substances / metabolism
Triglycerides / blood
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Caseins; 0/Lipids; 0/Thiobarbituric Acid Reactive Substances; 0/Triglycerides; 57-88-5/Cholesterol; EC 1.11.1.6/Catalase; EC 1.15.1.1/Superoxide Dismutase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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