Document Detail

The effects of undifferentiated spondyloarthropathy on left ventricular systolic and diastolic function.
MedLine Citation:
PMID:  23773639     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: Recent studies report that cardiovascular mortality is more common in patients with spondyloarthropathy (SpA) compared with the normal population. In this study, we aimed to determine left ventricular systolic and diastolic functions using tissue Doppler echocardiography (TDE) in addition to conventional methods in undifferentiated SpA (uSpA) patients.
METHODS: A total of 45 patients and 44 age and sex matched healthy controls participated in the present study. Left ventricular systolic and diastolic functions were assessed with two dimensional (2D) echocardiography, M-mode echocardiography, pulsed-wave (PW) echocardiography and tissue Doppler echocardiography. The peak systolic velocity (Sm), early diastolic myocardial peak velocity (Em), and late diastolic myocardial peak velocity (Am), myocardial isovolumetric contraction time (IVCTm), myocardial ejection time (ETm), myocardial isovolumetric relaxation time (IVRTm) and myocardial performance index (MPI) were measured at septal and lateral mitral annulus.
RESULTS: Left ventricular diastolic inflow velocities showed that isovolumetric relaxation time (IVRT) and deceleration time (DT) were significantly longer in the uSpA group. Left ventricular lateral wall PW tissue Doppler echocardiography showed that Em was significantly lower in uSpA group. Septal PW tissue Doppler echocardiography showed that Em was lower and IVRT was longer in the uSpA group compared with healthy controls.
CONCLUSION: In this study we determined that left ventricular systolic function is preserved in patients with uSpA. Although frequency of diastolic dysfunction was similar in both groups, deterioration of some diastolic parameters in the uSpA group might be considered for possible cardiac involvement in patients with uSpA.
Neslihan Albayrak; Nihal A Bayram; Sukran Erten; Cenk Sari; Telat Keles; Tahir Durmaz; Serdal Bastug; Engin Bozkurt
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Publication Detail:
Type:  Journal Article     Date:  2013-01-18
Journal Detail:
Title:  International journal of rheumatic diseases     Volume:  16     ISSN:  1756-185X     ISO Abbreviation:  Int J Rheum Dis     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-06-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101474930     Medline TA:  Int J Rheum Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  162-7     Citation Subset:  IM    
Copyright Information:
© 2013 The Authors International Journal of Rheumatic Diseases © 2013 Asia Pacific League of Associations for Rheumatology and Wiley Publishing Asia Pty Ltd.
Department of Cardiology, Ataturk Education and Research Hospital, Ankara, Turkey.
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