Document Detail

The effects of total unilateral occlusion vs. lid suture on the visual system of infant monkeys.
MedLine Citation:
PMID:  7251298     Owner:  NLM     Status:  MEDLINE    
To explore the premise that the immature primate visual system responds differently to total unilateral occlusion (no competitive abnormal binocular interaction) than it does to lid suture, one eye in two infant Macaca mulatta was completely occluded with optically opaque material. After a recovery period of 2 months, single cell responses from the striate cortex were recorded, and the lateral geniculate nuclei were examined histologically. Th results show that cortical and geniculate changes are comparable in severity to those found in earlier studies after unilateral lid suture.
G K von Noorden; M L Crawford
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Investigative ophthalmology & visual science     Volume:  21     ISSN:  0146-0404     ISO Abbreviation:  Invest. Ophthalmol. Vis. Sci.     Publication Date:  1981 Jul 
Date Detail:
Created Date:  1981-09-22     Completed Date:  1981-09-22     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7703701     Medline TA:  Invest Ophthalmol Vis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  142-6     Citation Subset:  IM; S    
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MeSH Terms
Amblyopia / physiopathology*
Evoked Potentials
Geniculate Bodies / cytology
Macaca mulatta
Photic Stimulation
Sensory Deprivation / physiology*
Vision, Ocular / physiology*
Visual Cortex / physiology
Grant Support
EY 01120/EY/NEI NIH HHS; RY 02520//PHS HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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