Document Detail

The effects of supplemental fish oil on blood pressure and morning cortisol in normotensive adults: a pilot study.
MedLine Citation:
PMID:  23104856     Owner:  NLM     Status:  In-Data-Review    
PURPOSE: To determine the effects of 6wk of supplementation with fish oil (FO) on blood pressure and the morning salivary cortisol concentration in normotensive adults.
METHODS: Testing was performed following an overnight fast. Subjects (n=40; 35+/-13y, mean+/-SD) rested supine for 40min, at which time blood pressure and heart rate were measured. Saliva was collected and analyzed for cortisol. Subjects were then randomly assigned to either: 4g/d of Safflower Oil (SO); or 4g/d of FO supplying 1,600mg/d eicosapentaenoic acid and 800mg/d docosahexaenoic acid. Testing was repeated following 6wk of treatment.
RESULTS: Compared to SO, there was a significant decrease in systolic blood pressure with FO (SO=1.3+/-5.8 mmHg; FO=-6.8+/-10.2 mmHg; p=0.004), a significant reduction in pulse pressure (SO=0.2+/-7.8 mmHg; FO=-6.4+/-8.8 mmHg; p=0.02), and a tendency for a decrease in mean arterial pressure (SO=1.2+/-5.3 mmHg; FO=-2.5+/-7.3 mmHg; p=0.08). There was a tendency for salivary cortisol to decrease with FO (SO=0.005+/-0.129 µg/dL; FO=-0.068+/-0.148 µg/dL; p=0.072), however, this change was not significantly correlated with the change in systolic blood pressure (r=0.021, p=0.929).
CONCLUSION: 6wk of supplementation with FO significantly decreases systolic blood pressure in normotensive adults and this change was not significantly correlated with a reduction in salivary cortisol.
Eric E Noreen; Josef Brandauer
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Publication Detail:
Type:  Journal Article     Date:  2012-10-23
Journal Detail:
Title:  Journal of complementary & integrative medicine     Volume:  9     ISSN:  1553-3840     ISO Abbreviation:  J Complement Integr Med     Publication Date:  2012  
Date Detail:
Created Date:  2012-10-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101313855     Medline TA:  J Complement Integr Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  IM    
Gettysburg College.
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