Document Detail


The effects of some anticholinergic compounds on the rabbit ureter.
MedLine Citation:
PMID:  897577     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Atropine, emeprone, and PR 197--a new anticholinergic compound--were examined for their possible effects on the rabbit ureter in situ. Ureteral pressure, recorded at two levels simultaneously, and intravesical pressure were studied. The effects of the substances were recorded in both normal (unobstructed) and obstructed ureters. It was found that all the substances, but especially PR 197, produced a fall in the basic intra-ureteral pressure, which was most pronounced in animals with obstructed ureters. PR 197 also temporarily abolished the ureteral peristalsis, while atropine and emeprone did not have this effect.
Authors:
C Sjögren; U Ulmsten
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of urology and nephrology     Volume:  11     ISSN:  0036-5599     ISO Abbreviation:  Scand. J. Urol. Nephrol.     Publication Date:  1977  
Date Detail:
Created Date:  1977-10-28     Completed Date:  1977-10-28     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0114501     Medline TA:  Scand J Urol Nephrol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  149-54     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Atropine / pharmacology
Emepronium / pharmacology
Muscle Contraction / drug effects
Parasympatholytics / pharmacology*
Pressure
Rabbits
Ureter / drug effects*,  physiology
Chemical
Reg. No./Substance:
0/Parasympatholytics; 27892-33-7/Emepronium; 51-55-8/Atropine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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