| The effects of smoking and zinc on the oxidative reactions of human neutrophils. | |
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MedLine Citation:
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PMID: 3029374 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Human neutrophils in whole blood and after isolation were examined for their capacity to produce superoxide anions when stimulated by zymosan. The isolation procedure caused neutrophils to lose some of this capacity. The neutrophils of smokers produced less particle-stimulated superoxide than those of non-smokers when the whole blood method was used but not when using isolated cells. Zinc inhibited this aspect of the respiratory burst of isolated neutrophils but enhanced it when the whole blood method was used. We emphasize the importance of methodology when interpreting results. |
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Authors:
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P H Beswick; P C Brannen; S S Hurles |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of clinical & laboratory immunology Volume: 21 ISSN: 0141-2760 ISO Abbreviation: J Clin Lab Immunol Publication Date: 1986 Oct |
Date Detail:
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Created Date: 1987-04-08 Completed Date: 1987-04-08 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7808987 Medline TA: J Clin Lab Immunol Country: ITALY |
Other Details:
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Languages: eng Pagination: 71-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cell Separation / methods Humans N-Formylmethionine Leucyl-Phenylalanine / pharmacology Neutrophils / drug effects, metabolism* Smoking* Superoxides / blood* Zinc / pharmacology* Zymosan / pharmacology |
| Chemical | |
Reg. No./Substance:
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11062-77-4/Superoxides; 59880-97-6/N-Formylmethionine Leucyl-Phenylalanine; 7440-66-6/Zinc; 9010-72-4/Zymosan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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