| The effects of sex-steroids on the synthesis of uterine non-histone proteins. | |
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MedLine Citation:
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PMID: 832765 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Newly synthesized non-histone proteins (NHP) labelled with [35S] methionine were isolated from uterine epithelium and stroma after different hormone treatments and examined by isoelectric focusing in polyacrylamide gels. Progesterone increased the proportion of basic NHP in the epithelium. This effect was detectable within 4 h and was maintained unchanged after oestrogen stimulation, which increased the synthesis of all classes of NHP. The proportion of basic NHP was higher in the untreated stroma than in the epithelium. Progesterone pretreatment did not increase the proportion of basic NHP in the stroma but prevented the increase in the more acidic NHP which followed treatment with oestrogen alone. The tendency to synthesize a higher proportion of basic NHP did not in any way correlate with the tissue's proliferative status. |
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Authors:
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J W Pollard; L Martin |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Molecular and cellular endocrinology Volume: 6 ISSN: 0303-7207 ISO Abbreviation: Mol. Cell. Endocrinol. Publication Date: 1977 Jan |
Date Detail:
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Created Date: 1977-03-21 Completed Date: 1977-03-21 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7500844 Medline TA: Mol Cell Endocrinol Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 223-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Castration Cell Nucleus / drug effects, metabolism Chromosomal Proteins, Non-Histone / biosynthesis* Estradiol / pharmacology* Female Mice Progesterone / pharmacology* Uterus / drug effects, metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Chromosomal Proteins, Non-Histone; 50-28-2/Estradiol; 57-83-0/Progesterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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