Document Detail


The effects of repetitive compression on nerve conduction and blood flow in the rabbit sciatic nerve.
MedLine Citation:
PMID:  20444785     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The objective of this study was to clarify the effect of repetitive compression on nerve physiology in an experimental rabbit model. We defined 80 mmHg as a compression force which caused temporary disturbance of nerve conduction and blood flow with a brief compression. The following compressions were applied for 30 minutes to rabbit sciatic nerves: continuous compression, low frequency release compression (1 second of release time every 30 seconds) and high frequency release compression (1 second of release time every 10 seconds). Compound nerve action potentials and nerve blood flow were evaluated from the start of compression until 30 minutes after release. Endoneurial microvascular permeability was evaluated with Evans Blue albumin. The repetitive compression groups showed delay in recovery of compound nerve action potentials and blood flow after release, with endoneurial oedema. These findings suggest that repetitive compression may increase the risk of breakdown of the blood nerve barrier.
Authors:
Y Yoshii; Y Nishiura; N Terui; Y Hara; Saijilafu; Naoyuki Ochiai
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-08-17
Journal Detail:
Title:  The Journal of hand surgery, European volume     Volume:  35     ISSN:  1532-2211     ISO Abbreviation:  J Hand Surg Eur Vol     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-06     Completed Date:  2010-09-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101315820     Medline TA:  J Hand Surg Eur Vol     Country:  England    
Other Details:
Languages:  eng     Pagination:  269-78     Citation Subset:  IM    
Affiliation:
Department of Orthopaedic Surgery, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki 305-8575, Japan. yy12721@yahoo.co.jp
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MeSH Terms
Descriptor/Qualifier:
Action Potentials / physiology
Animals
Capillary Permeability / physiology
Cumulative Trauma Disorders / complications,  physiopathology*
Disease Models, Animal
Male
Nerve Compression Syndromes / etiology*,  physiopathology
Neural Conduction / physiology*
Rabbits
Recovery of Function / physiology
Regional Blood Flow / physiology*
Sciatic Nerve / blood supply*,  physiopathology*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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