Document Detail

The effects of radiofrequency ablation on left atrial systolic function in patients with atrioventricular nodal reentrant and atrioventricular reentrant tachycardias.
MedLine Citation:
PMID:  21332047     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Recurrent supraventricular arrhythmias may cause remodelling of the atria. The effects of radiofrequency (RF) ablation of these arrhythmias on left atrial function have not been well established.
AIM: To evaluate the effects of RF ablation on left atrial systolic function in patients with atrioventricular nodal reentrant tachycardia (AVNRT) and atrioventricular tachycardia (AVRT).
METHODS: The study group consisted of 70 patients (22 men), in whom successful RF ablation of slow pathway (35 patients) or accessory pathway (35 patients) was performed. Patients with atrial fibrillation, structural heart disease, ventricular arrhythmias (> class 3 Lown), impaired left ventricular systolic function or on antiarrhythmics were excluded. All the patients had echocardiographic study before and 6 months after ablation. Left atrial systolic function was assessed using atrial ejection force (AEF) according to Manning's formula (AEF = 0.5 x ρ x MA x A(2), r: blood density = 1.06 g/cm(3), MA: mitral orifice area [cm(2)], A: A wave velocity). The following left atrial dimensions were assessed: antero-posterior (LA-AP), infero-superior (LA-IS, long axis), medio-lateral (LA-ML, short axis). The correlations between AEF and electrophysiological parameters were analysed (VA - ventriculo-atrial conduction, VA/CL - tachycardia cycle length).
RESULTS: The AEF increased significantly in the AVNRT group (7.78 vs 10.75 kdynes; p < 0.001) whereas it did not change in the AVRT group (8.96 vs 9.50, NS). Left atrial dimensions decreased significantly in both groups (AVNRT group: LA-AP: 38 vs 34 mm; LA-ML: 37 vs 33 mm; LA-IS: 51 vs 45 mm; p < 0.001; AVRT group: LA-AP: 38 vs 36 mm; p < 0.01; LA-ML: 37 vs 35 mm, p < 0.001; LA-IS: 50 vs 46 mm; p < 0.001). There was a significant correlation between the increment of AEF and electrophysiological parameters of the tachycardia (VA, r = -0.51 and VA/CL, r = -0.53).
CONCLUSIONS: 1. RF ablation of AVNRT is associated with the improvement of left atrial systolic function. 2. Left atrial size decreases following RF ablation of both AVNRT and AVRT. 3. The effects of RF ablation on the left atrial systolic function depends on electrophysiological parameters of the tachycardia (VA and VA/CL).
Jacek Majewski; Jacek Lelakowski; Dominik Jędrzejowski
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Kardiologia polska     Volume:  69     ISSN:  0022-9032     ISO Abbreviation:  Kardiol Pol     Publication Date:  2011  
Date Detail:
Created Date:  2011-02-18     Completed Date:  2011-06-23     Revised Date:  2014-07-30    
Medline Journal Info:
Nlm Unique ID:  0376352     Medline TA:  Kardiol Pol     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  116-22     Citation Subset:  IM    
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MeSH Terms
Atrial Function, Left
Catheter Ablation*
Heart Atria / physiopathology*
Middle Aged
Tachycardia, Atrioventricular Nodal Reentry / surgery*
Treatment Outcome
Comment In:
Kardiol Pol. 2011;69(2):123-4   [PMID:  21332048 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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