Document Detail

The effects of progressive exercise on cardiovascular function in elite athletes: Focus on oxidative stress.
MedLine Citation:
PMID:  21388931     Owner:  NLM     Status:  In-Data-Review    
Some side-effects of excessive physical training are ascribed to reactive oxygen species production. In this work we investigated the effects of progressively imposed maximal physical effort (levels I to V), using progressive maximal exercise test, on peripheral blood lactate, NO (through NO2-), superoxide anion (O2-) and methemoglobin (MetHb) in a group of 19 elite soccer players. Blood lactate (mmol/L) was increased (4.55, level V vs. resting level, 1.95). The basal production of NO2- was in the direct relation with O2 consumption. Significant increase (p<0.05) in O2- values at effort level I (4.18) as compared to the resting value (4.01), and the significant increase (p<0.01 or p<0.05) in the MetHb (%) was found between II (18.79) and III (19.63) or between II and IV (19.24) effort levels, respectively. The regression lines of NO2- and O2- crossed at the level of the respiratory compensation point (RC), suggesting that RC could be of a crucial importance not only in the anaerobic and aerobic metabolism but in mechanisms of signal transductions as well. The results could be of the theoretical interest and also useful in designing an athlete training strategy.
Vladimir Lj Jakovljević; M Zlatković; D Cubrilo; I Pantić; D M Djurić
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta physiologica Hungarica     Volume:  98     ISSN:  0231-424X     ISO Abbreviation:  Acta Physiol Hung     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309201     Medline TA:  Acta Physiol Hung     Country:  Hungary    
Other Details:
Languages:  eng     Pagination:  51-8     Citation Subset:  IM    
University of Kragujevac Department of Physiology, The Faculty of Medicine Kragujevac Serbia University of Kragujevac Department of Physiology, Faculty of Medicine Svetozara Markovica 69 P. P. 124 34000 Kragujevac Republic of Serbia.
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