| The effects of privet exposure on asthma morbidity. | |
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MedLine Citation:
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PMID: 7715885 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To determine whether privet may be an important cause of asthma morbidity. METHODS: The study was conducted in two parts; (1) a longitudinal study of asthma symptoms, medication use, peak expiratory flow rate and airway responsiveness during and after the privet-flowering season, and (2) bronchial challenge of 17 subjects with two species of flowering privet. Subjects were asthmatics who attributed worsening asthma symptoms to privet exposure. All subjects were atopic and had perennial asthma symptoms requiring treatment with inhaled steroids and beta agonists. RESULTS: 1. Twenty subjects completed the longitudinal study. Airway responsiveness (PD20 histamine) was significantly greater during the privet-flowering season (0.4 mumol vs 0.73 mumol, p < 0.05). Symptom scores and bronchodilator use were higher and peak expiratory flow rates lower during the privet-flowering season, but the changes were small and not statistically significant. 2. Seventeen subjects from the longitudinal study subsequently had bronchial challenge studies performed. There were no isolated early responses, but six had late asthmatic responses. Eleven had no airway constrictor response to challenge with either of the two local varieties of privet. CONCLUSION: Although significant increases in airway responsiveness occur during the privet flowering season, only a proportion of this highly select group had a constrictor response to direct challenge. Privet exposure may cause bronchoconstriction in certain individuals, but it is unlikely to be responsible for a large proportion of asthma morbidity in New Zealand. |
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Authors:
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G Richards; J Kolbe; J Fenwick; H Rea |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The New Zealand medical journal Volume: 108 ISSN: 0028-8446 ISO Abbreviation: N. Z. Med. J. Publication Date: 1995 Mar |
Date Detail:
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Created Date: 1995-05-16 Completed Date: 1995-05-16 Revised Date: 2010-03-24 |
Medline Journal Info:
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Nlm Unique ID: 0401067 Medline TA: N Z Med J Country: NEW ZEALAND |
Other Details:
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Languages: eng Pagination: 96-9 Citation Subset: IM |
Affiliation:
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Department of Respiratory Medicine, Green Lane Hospital, Auckland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Asthma / diagnosis, etiology* Bronchial Provocation Tests Forced Expiratory Volume Humans Longitudinal Studies Middle Aged New Zealand Peak Expiratory Flow Rate Pollen* Skin Tests Trees |
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