Document Detail

The effects of postural changes of baroreflex gain in normal and hypertensive pregnancies.
MedLine Citation:
PMID:  11848166     Owner:  NLM     Status:  MEDLINE    
In order to understand the changes of baroreflex gain due to postural changes in normal pregnancies, we measured percentage changes (% changes) in blood pressure (SBP, DBP), heart rate (HR), stroke volume (SV), cardiac output (CO), total peripheral resistance (TPR) as well as cardiac autonomic nervous function (HF as an index of parasympathetic and LF/HF as an index of sympathetic function) and compared these parameters in normal pregnancies with those found in hypertensive pregnancies, such as chronic hypertensive (CHP) and severe preeclamptic pregnancies (PE), in late pregnancy (after 32 wks). When the position was changed from supine to standing in normal and non-pregnant women, the % changes of HR, DBP, TPR and LF/HF were increased and SBP, SV, CO and HF were decreased. The % changes of these parameters, however, were gradually decreased as pregnancy progressed, especially after 20-24 wks of gestation. In hypertensive pregnancies, however, even in late pregnancy, the decreased SBP and increased TPR was still observed and the profound decrease of CO and SV and increase of TPR were characteristic in PE when compared to CHP.
Yoshiaki Miyake; Miyako Ohnishi; T K Fujii; Tatsuo Yamamoto; Chika Yoneda; Sachie Takahashi; Yuhei Ichimaru
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical and experimental hypertension (New York, N.Y. : 1993)     Volume:  24     ISSN:  1064-1963     ISO Abbreviation:  Clin. Exp. Hypertens.     Publication Date:    2002 Jan-Feb
Date Detail:
Created Date:  2002-02-18     Completed Date:  2002-07-31     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9305929     Medline TA:  Clin Exp Hypertens     Country:  United States    
Other Details:
Languages:  eng     Pagination:  23-31     Citation Subset:  IM    
Nihon University School of Medicine, Nerima Hikarigaoka Hospital, Tokyo, Japan.
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MeSH Terms
Baroreflex / physiology*
Heart Conduction System / physiopathology
Hypertension / physiopathology*
Longitudinal Studies
Posture / physiology*
Pregnancy Complications, Cardiovascular / physiopathology*
Reference Values

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