Document Detail

The effects of parental immunoreactivity on pregnancy, birth, and cognitive development: maternal immune attack on the fetus?
MedLine Citation:
PMID:  1395648     Owner:  NLM     Status:  MEDLINE    
The effects of parental immunoreactivity were tested in two ways on questionnaire data collected from 468 children and their families. (1) It was found that the presence of learning difficulties in boys was associated with pregnancy and birth complications, as well as with maternal immunoreactivity. Paternal immunoreactivity did not appear to be related to any of the variables in question. (2) The antecedent brother effect, that children, particularly males, with older brothers have higher rates of the same set of variables, was not found. Maternal immunoreactivity emerges as a risk factor for pregnancy, birth, and cognitive development, but not exclusively by the proposed mechanism of maternal immune attack on the fetus.
S G Crawford; B J Kaplan; M Kinsbourne
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cortex; a journal devoted to the study of the nervous system and behavior     Volume:  28     ISSN:  0010-9452     ISO Abbreviation:  Cortex     Publication Date:  1992 Sep 
Date Detail:
Created Date:  1992-11-04     Completed Date:  1992-11-04     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0100725     Medline TA:  Cortex     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  483-91     Citation Subset:  IM    
Department of Psychology, University of Calgary.
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MeSH Terms
Autoimmune Diseases / diagnosis,  genetics*,  immunology
Brain / immunology
Brain Damage, Chronic / diagnosis,  genetics*,  immunology
Hypersensitivity / diagnosis,  genetics*,  immunology
Infant, Newborn
Intelligence / genetics*,  physiology
Learning Disorders / diagnosis,  genetics,  immunology
Pregnancy Complications / diagnosis,  immunology*
Prenatal Exposure Delayed Effects*
Risk Factors

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