Document Detail

The effects of oral iron supplementation on zinc and magnesium levels during pregnancy.
MedLine Citation:
PMID:  4041396     Owner:  NLM     Status:  MEDLINE    
Serial changes in serum zinc and magnesium concentrations have been studied before conception, throughout pregnancy and at 12 weeks postpartum in 15 normal healthy women not receiving iron supplementation, 10 women receiving iron supplementation but otherwise having healthy pregnancies and five insulin-dependent diabetics who also received oral iron. Relative to pre-pregnancy values zinc concentrations progressively decreased throughout pregnancy reaching a nadir at 36 weeks gestation followed by an increase; pre-pregnancy values were achieved by 12 weeks postpartum. Magnesium concentrations also decreased throughout pregnancy reaching a nadir at 32 weeks gestation increasing thereafter again with pre-pregnancy values achieved by 12 weeks postpartum. Iron supplementation in non-diabetic and diabetic women had no significant effect upon the changes in serum concentration of either zinc or magnesium. These results suggest that the decrease in the concentrations of both elements is a normal physiological adjustment to pregnancy and that iron supplementation does not influence these changes.
W L Sheldon; M O Aspillaga; P A Smith; T Lind
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of obstetrics and gynaecology     Volume:  92     ISSN:  0306-5456     ISO Abbreviation:  Br J Obstet Gynaecol     Publication Date:  1985 Sep 
Date Detail:
Created Date:  1985-11-21     Completed Date:  1985-11-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7503752     Medline TA:  Br J Obstet Gynaecol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  892-8     Citation Subset:  AIM; IM    
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MeSH Terms
Administration, Oral
Diabetes Mellitus, Type 1 / blood
Iron / administration & dosage*
Longitudinal Studies
Magnesium / blood*
Postpartum Period
Pregnancy Trimester, Third
Pregnancy in Diabetics / blood
Zinc / blood*
Reg. No./Substance:
7439-89-6/Iron; 7439-95-4/Magnesium; 7440-66-6/Zinc

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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