| The effects of norepinephrine infusion on oxygen consumption in a patient with septic shock. | |
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MedLine Citation:
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PMID: 2332540 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 65-year-old man developed postsurgical septic shock, unresponsive to plasma volume expansion and administration of dopamine and dobutamine. A continuous norepinephrine infusion was then started and the dose increased to 0.62 micrograms.kg-1.min-1 until the mean arterial pressure was 70 mmHg. Prior to and during the norepinephrine infusion, oxygen consumption was continuously measured with a mass spectrometer system. There was a parallel increase in mean arterial pressure and oxygen consumption (+ 35%). There was also an increase in cardiac index and oxygen delivery. Systemic vascular resistance was only transiently increased. In this case with septic shock, norepinephrine infusion improved hemodynamic variables with an associated increase in oxygen consumption. |
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Authors:
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Y Bouffard; S Tissot; J P Viale; B Delafosse; G Annat; P Bachmann; J Motin |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Intensive care medicine Volume: 16 ISSN: 0342-4642 ISO Abbreviation: Intensive Care Med Publication Date: 1990 |
Date Detail:
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Created Date: 1990-06-07 Completed Date: 1990-06-07 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7704851 Medline TA: Intensive Care Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 133-4 Citation Subset: IM |
Affiliation:
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Service de Réanimation, Hospices Civils de Lyon, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Calorimetry, Indirect Hemodynamics / drug effects Humans Infusions, Intravenous Male Mass Spectrometry Norepinephrine / administration & dosage, pharmacology*, therapeutic use Oxygen Consumption / drug effects* Shock, Septic / drug therapy*, physiopathology |
| Chemical | |
Reg. No./Substance:
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51-41-2/Norepinephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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