Document Detail


The effects of muscle hypotonia and weakness on balance: A study on Prader-Willi and Ehlers-Danlos syndrome patients.
MedLine Citation:
PMID:  21306869     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Prader-Willi syndrome (PWS) and Ehlers-Danlos syndrome (EDS) are two different genetical disorders both characterized, among other features, by muscular hypotonia. Postural control seems to be impaired in both conditions. The aim of the present study was to quantitatively compare postural control in adult PWS and EDS using stabilometric platform to unveil possible common determinants of impaired balance. We enrolled 11 PWS and 21 EDS adult patients and 20 age-matched controls. They were instructed to maintain an upright standing position for 30s with open eyes (OEs) focusing on a 6cm black circle positioned at a distance of 1.5m. Both PWS and EDS patients were characterized by higher RANGEML, RANGEAP and trajectory length of CoP values as compared to CG. No statistically differences were found between PWS and EDS in terms of any of these parameters. The results demonstrated that both PWS and EDS are characterized by a severe postural instability. Muscle hypotonia and weakness may account for reduced balance capacity. Quantitative characterization of instability is important to identify, develop and enhance rehabilitation interventions.
Authors:
Manuela Galli; Veronica Cimolin; Luca Vismara; Graziano Grugni; Filippo Camerota; Claudia Celletti; Giorgio Albertini; Chiara Rigoldi; Paolo Capodaglio
Related Documents :
8459969 - The role of velamentous cord insertion in the etiology of twin-twin transfusion syndrome.
2688729 - An historical look at the thoracic outlet compression syndrome.
21749729 - Monitoring serum il-18 levels is useful for treatment of a patient with systemic juveni...
3041839 - Corneal metastatic calcification in werner's syndrome.
11444739 - Color doppler and duplex sonography in 5 patients with thoracic outlet syndrome.
9002419 - Bilateral rudimentary first ribs as a cause of thoracic outlet syndrome.
21139409 - Association between meat consumption and carotid intima-media thickness in korean adult...
19969199 - Unusual compression neuropathies of the forearm, part i: radial nerve.
21624989 - Sensory neuropathy as part of the cerebellar ataxia neuropathy vestibular areflexia syn...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-2-7
Journal Detail:
Title:  Research in developmental disabilities     Volume:  -     ISSN:  1873-3379     ISO Abbreviation:  -     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-2-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8709782     Medline TA:  Res Dev Disabil     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Affiliation:
Bioeng. Dept., Politecnico di Milano, p.zza Leonardo Da Vinci 32, 20133 Milano, Italy; IRCCS "San Raffaele Pisana", Tosinvest Sanità, Roma, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Visual feedback of the non-moving limb improves active joint-position sense of the impaired limb in ...
Next Document:  Graded Motor Imagery.