Document Detail

The effects of multiple gestation and selective reduction on fetal outcome.
MedLine Citation:
PMID:  8106941     Owner:  NLM     Status:  MEDLINE    
A group of 32 women with at least 3 or more viable fetuses by sonography at approximately 8 weeks gestation were given the option of selective reduction. They were advised that this was a relatively new procedure but heretofore in a small series was not associated with a significant increase in fetal demise. Only 7 of 32 women chose this option. six of these 7 had triplets reduced to twins, 1 woman had quadruplets reduced to twins. Thirteen of 14 viable babies were successfully delivered at a mean of 36.8 weeks gestation; 2 of 7 (28.6%) delivered before 37 weeks. In contrast, 7 of 25 (24%) not having reduction lost all babies (6 triplets, 1 quadruplet). Four other women lost at least 1 of their gestations (total of 5 babies). Pre-term deliveries (< 37 weeks) occurred in 16 of 18 (88.8%) patients delivering at least 1 live baby, with a mean of 33.7 weeks gestation. Thus the high rate of total fetal loss and prematurity for multiple gestation and the low pregnancy wastage and pre-term delivery rate following selective reduction might make the latter a reasonable therapeutic option to patients interested in having the best chance of delivering healthy viable babies.
J H Check; K Nowroozi; B Vetter; A Rankin; C Dietterich; B Schubert
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  21     ISSN:  0300-5577     ISO Abbreviation:  J Perinat Med     Publication Date:  1993  
Date Detail:
Created Date:  1994-03-22     Completed Date:  1994-03-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  299-302     Citation Subset:  IM    
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, New Jersey.
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MeSH Terms
Abortion, Therapeutic / adverse effects*
Chi-Square Distribution
Fetal Death / etiology
Obstetric Labor, Premature / etiology
Pregnancy Outcome*
Pregnancy Trimester, First
Pregnancy, Multiple*
Ultrasonography, Prenatal

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