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The effects of low-level prenatal lead exposure on birth outcomes.
MedLine Citation:
PMID:  23321271     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Exposure to lead early in life may be a risk factor for fetal growth, but little is known about the effects of low-level prenatal lead exposure on birth outcomes. We measured maternal and cord blood lead levels and examined their associations with birth outcomes. Mother-infant pairs (n = 252) were recruited from a rural area located on the south coast of Laizhou Bay between 2010 and 2011. The median levels of maternal and cord blood lead were 3.20 and 2.52 μg/dL, respectively. Increasing maternal blood lead exposure was associated with decreasing birth weight (β = -148.99; 95% CI, -286.33 to -11.66), and a significant negative relationship was found between cord blood lead levels and birth length (β = -0.84; 95% CI, -1.52 to -0.16). Low-level prenatal lead exposure may adversely affect fetal growth. These results may be important for public health and have implications regarding the recommended blood lead levels.
Authors:
Xin Xie; Guodong Ding; Chang Cui; Limei Chen; Yu Gao; Yijun Zhou; Rong Shi; Ying Tian
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-11
Journal Detail:
Title:  Environmental pollution (Barking, Essex : 1987)     Volume:  175C     ISSN:  1873-6424     ISO Abbreviation:  Environ. Pollut.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804476     Medline TA:  Environ Pollut     Country:  -    
Other Details:
Languages:  ENG     Pagination:  30-34     Citation Subset:  -    
Copyright Information:
Copyright © 2013 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Environmental Health, School of Public Health, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai 200025, China; MOE and Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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