| The effects of iron deficiency anemia on p wave duration and dispersion. | |
| | |
MedLine Citation:
|
PMID: 21243273 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
OBJECTIVES: The association between P wave dispersion and iron deficiency anemia has not been documented in the literature. In this study, we evaluated P wave dispersion in patients with iron deficiency anemia and the possible relationships between P wave dispersion and other echocardiographic parameters. INTRODUCTION: The iron status of an individual may play an important role in cardiovascular health. Anemia is an independent risk factor for adverse cardiovascular outcomes. P wave dispersion is a simple electrocardiographic marker that has a predictive value for the development of atrial fibrillation. Apart from cardiovascular diseases, several conditions, such as seasonal variation, alcohol intake and caffeine ingestion, have been demonstrated to affect P wave dispersion. METHODS: The study included 97 patients who had iron deficiency anemia and 50 healthy subjects. The cases were evaluated with a clinical examination and diagnostic tests that included 12-lead electrocardiography and transthoracic echocardiography. RESULTS: Compared to the control group, patients with iron deficiency anemia showed significantly longer maximum P wave duration (Pmax) (91.1±18.0 vs. 85.8±6.7 msec, p=0.054), P wave dispersion (PWD) (48.1±7.7 vs. 40.9±5.6 msec, p<0.001), mitral inflow deceleration time (DT) (197.5±27.9 vs. 178.8±8.9 msec, p<0.001) and isovolumetric relaxation time (IVRT) (93.3±9.2 vs. 77.4±8.2 msec, p<0.001); they also showed increased heart rate (85.7±16.1 vs. 69.0±4.4, p<0.001) and frequency of diastolic dysfunction (7 (7.2%) vs. 0). Correlation analysis revealed that PWD was significantly correlated with IVRT, DT, heart rate, the presence of anemia and hemoglobin level. CONCLUSIONS: Iron deficiency anemia may be associated with prolonged P wave duration and dispersion and impaired diastolic left ventricular filling. |
| | |
Authors:
|
Hakki Simsek; Yilmaz Gunes; Cengiz Demir; Musa Sahin; Hasan Ali Gumrukcuoglu; Mustafa Tuncer |
Related Documents
:
|
15195053 - Concurrent laryngeal abnormalities in patients with paradoxical vocal fold dysfunction. 8425433 - Comparison of stationary vs ambulatory 24-hour ph monitoring systems in diagnosis of ga... 23112353 - Prevalence of metabolic syndrome in south indian patients with psoriasis vulgaris and t... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Clinics (São Paulo, Brazil) Volume: 65 ISSN: 1980-5322 ISO Abbreviation: Clinics (Sao Paulo) Publication Date: 2010 |
Date Detail:
|
Created Date: 2011-01-18 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101244734 Medline TA: Clinics (Sao Paulo) Country: Brazil |
Other Details:
|
Languages: eng Pagination: 1067-71 Citation Subset: IM |
Affiliation:
|
Cardiology Department, Faculty of Medicine, Yuzuncu Yil University, Turkey. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Aberrant signaling pathways in medulloblastomas: a stem cell connection.
Next Document: The progins progesterone receptor gene polymorphism is not related to endometriosis-associated infer...