Document Detail


The effects of intravitreal ophthalmic medications on intraocular pressure.
MedLine Citation:
PMID:  19373694     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ophthalmic medications are often given as intravitreal injection. Antimicrobials, antivirals, corticosteroids and anti- vascular endothelial growth factor agents are the main classes which can be administered through intravitreal injections. Possible complications of intravitreal injection include intraocular pressure changes, especially intraocular pressure elevations. This review discusses both injection-related intraocular pressure elevations which can occur immediately after injection of any kind of medication and drug specific-related intraocular pressure changes which may be detected days or even months after the injection.
Authors:
Huijuan Wu; Teresa C Chen
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in ophthalmology     Volume:  24     ISSN:  1744-5205     ISO Abbreviation:  Semin Ophthalmol     Publication Date:    2009 Mar-Apr
Date Detail:
Created Date:  2009-04-17     Completed Date:  2009-05-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8610759     Medline TA:  Semin Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  100-5     Citation Subset:  IM    
Affiliation:
Glaucoma Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
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MeSH Terms
Descriptor/Qualifier:
Angiogenesis Inhibitors / administration & dosage,  adverse effects
Antibodies, Monoclonal / administration & dosage,  adverse effects
Humans
Injections / adverse effects
Intraocular Pressure / drug effects*
Ophthalmic Solutions / administration & dosage*,  adverse effects*
Vascular Endothelial Growth Factor A / antagonists & inhibitors
Vitreous Body
Chemical
Reg. No./Substance:
0/Angiogenesis Inhibitors; 0/Antibodies, Monoclonal; 0/Ophthalmic Solutions; 0/Vascular Endothelial Growth Factor A; 0/bevacizumab; 0/ranibizumab

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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