| The effects of intravenous clonidine on ventilation. | |
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MedLine Citation:
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PMID: 1909506 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effects of clonidine, an alpha 2 adrenergic agonist, on ventilation were studied in a group of adult volunteers. The ventilatory variables measured were minute ventilation, respiratory rate, end-tidal carbon dioxide tension and the response to carbon dioxide challenge. We found no differences in minute ventilation, respiratory rate and end-tidal carbon dioxide tension, before and after clonidine administration. However, the ventilatory response to carbon dioxide was significantly attenuated following clonidine, suggesting that clonidine has respiratory depressant effects. |
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Authors:
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R Ooi; J Pattison; S A Feldman |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Anaesthesia Volume: 46 ISSN: 0003-2409 ISO Abbreviation: Anaesthesia Publication Date: 1991 Aug |
Date Detail:
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Created Date: 1991-10-08 Completed Date: 1991-10-08 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370524 Medline TA: Anaesthesia Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 632-3 Citation Subset: AIM; IM |
Affiliation:
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Magill Department of Anaesthetics, Westminster Hospital, London. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Pressure / drug effects Carbon Dioxide Clonidine / administration & dosage, pharmacology* Depression, Chemical Drug Evaluation Female Heart Rate / drug effects Humans Injections, Intravenous Male Respiration / drug effects* |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide; 4205-90-7/Clonidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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