Document Detail

The effects of intraaortic balloon counterpulsation on myocardial infarct size.
MedLine Citation:
PMID:  116607     Owner:  NLM     Status:  MEDLINE    
The left anterior descending coronary artery was ligated in 6 baboons. Subsequently, 3 animals were supported with long-term (24-hour) intraaortic balloon pumping (IABP), and 3 were on coronary occlusion alone. Animals were studied hemodynamically and with unipolar electrocardiographic mapping acutely and then were studied after a week and killed. A histological measurement of infarct size was made. The use of IABP had no influence on the area of ischemia determined by unipolar mapping or on infarct size measured quantitatively at a week. Similarly, there were no acute hemodynamic differences between the two groups. The only significant difference noted was a reduction in systolic pressure in IABP animals during balloon pumping and a significantly higher left ventricular systolic pressure a week following infarction in animals treated with IABP. The data indicate no significant effect of IABP on altering infarct size in animals with acute coronary ligation in the absence of cardiogenic shock.
H H Haston; J J McNamara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  28     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1979 Oct 
Date Detail:
Created Date:  1980-01-19     Completed Date:  1980-01-19     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  335-41     Citation Subset:  AIM; IM    
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MeSH Terms
Assisted Circulation*
Coronary Circulation
Coronary Vessels / surgery
Disease Models, Animal
Intra-Aortic Balloon Pumping*
Myocardial Contraction
Myocardial Infarction / pathology,  therapy*

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