Document Detail


The effects of ingested and intravenous glucose on forearm uptake of glucose and glucogenic substrate in normal man.
MedLine Citation:
PMID:  6642087     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The forearm uptake of glucose, lactate, and alanine was determined in overnight fasted man following both oral glucose loading and the intravenous (i.v.) infusion of glucose in an absorption pattern. Arterial glucose concentrations were lower following oral than following i.v. loading and forearm glucose uptake was 50% higher after oral glucose. Arterial insulin levels were higher in the first 2 h during oral loading. Forearm lactate and pyruvate production did not change significantly during glucose administration by either route so that the increased plasma levels are due to splanchnic production.
Authors:
J Radziuk; R Inculet
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Diabetes     Volume:  32     ISSN:  0012-1797     ISO Abbreviation:  Diabetes     Publication Date:  1983 Nov 
Date Detail:
Created Date:  1984-01-26     Completed Date:  1984-01-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372763     Medline TA:  Diabetes     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  977-81     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Adult
Blood Glucose / metabolism
Female
Forearm / blood supply,  metabolism
Gluconeogenesis*
Glucose / administration & dosage,  metabolism*
Humans
Infusions, Parenteral
Lactates / metabolism
Lactic Acid
Liver Glycogen / biosynthesis
Male
Pyruvates / metabolism
Pyruvic Acid
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Lactates; 0/Liver Glycogen; 0/Pyruvates; 127-17-3/Pyruvic Acid; 50-21-5/Lactic Acid; 50-99-7/Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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