Document Detail

The effects of in utero diagnostic X-irradiation on the development of preschool-age children.
MedLine Citation:
PMID:  8631646     Owner:  NLM     Status:  MEDLINE    
High doses of X-irradiation may affect the developing human embryo and fetus, causing brain, eye, skeletal and other defects. Although the doses used in diagnostic irradiation are not considered to be high enough to cause fetal anomalies, it is unknown whether they affect the long-term development of the in utero exposed children. Using the Bayley or McCarthy developmental scales we examined 52 children born to mothers exposed to diagnostic X-irradiation of the abdomen and/or pelvis during the first trimester of pregnancy, 60 children born to mothers exposed during pregnancy (58 in the first trimester) to X-rays in areas other than the abdomen or pelvis, and 62 normal children without maternal exposure to X-rays during pregnancy. All children were aged 1-5 years at examination. Parental socioeconomic status was the same in all three groups. There were no differences in the results of the medical and neurological examination, and in the motor or congnitive scores among three groups. Embryonic or fetal exposure to X-irradiation in doses below 5 rads does not seem to have any effect on development during childhood.
A Ornoy; N Patlas; L Schwartz
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Israel journal of medical sciences     Volume:  32     ISSN:  0021-2180     ISO Abbreviation:  Isr. J. Med. Sci.     Publication Date:  1996 Feb 
Date Detail:
Created Date:  1996-07-03     Completed Date:  1996-07-03     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0013105     Medline TA:  Isr J Med Sci     Country:  ISRAEL    
Other Details:
Languages:  eng     Pagination:  112-5     Citation Subset:  IM    
Laboratory of Teratology, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
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MeSH Terms
Age Factors
Child Development*
Child, Preschool
Embryo, Mammalian / radiation effects*
Fetus / radiation effects*
Prenatal Diagnosis*
Prenatal Exposure Delayed Effects*
Radiation Dosage
Radiography / adverse effects*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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