Document Detail

The effects of immobilization on the primate temporomandibular joint: a histologic and histochemical study.
MedLine Citation:
PMID:  6174716     Owner:  NLM     Status:  MEDLINE    
The effects of prolonged immobilization on the primate temporomandibular joint (TMJ) condylar cartilage are reported. After eight weeks of immobilization, changes were assayed histochemically using the specific glycosaminoglycan (GAG) stain safranin O. Following the immobilization period, the articulating cartilage showed marked thinning, disorganization, and loss of the superficial GAG stain. After two weeks of remobilization, further thinning had occurred and GAG staining was nearly absent. Sections from condyles of animals sacrificed serially from two weeks to eight months after immobilization showed a gradual return to the thickness and GAG content of the control animals' condyles. But even at this stage, GAG staining was less marked than in the controls, and zonal reorganization was incomplete. These results suggest that TMJ immobilization is not wholly benign procedure.
R W Glineburg; D M Laskin; D I Blaustein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons     Volume:  40     ISSN:  0278-2391     ISO Abbreviation:  J. Oral Maxillofac. Surg.     Publication Date:  1982 Jan 
Date Detail:
Created Date:  1982-05-12     Completed Date:  1982-05-12     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8206428     Medline TA:  J Oral Maxillofac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  3-8     Citation Subset:  D; IM; S    
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MeSH Terms
Cartilage, Articular / pathology*
Macaca fascicularis
Mandibular Condyle / pathology
Staining and Labeling
Temporomandibular Joint / pathology*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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