Document Detail


The effects of hypothermia on a cloned human brain glutamate transporter (hGLT-1) expressed in Chinese hamster ovary cells: -[3H]L-glutamate uptake study.
MedLine Citation:
PMID:  10589646     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
IMPLICATIONS: Under certain pathologic conditions, including cerebral ischemia and traumatic brain injury, glutamate neurotoxicity may initially be propagated by hypothermia due to relative failure of glutamate uptake via Human Glial Glutamate Transporter before a subsequent recovery of uptake.
Authors:
F Sakai; K Amaha
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  89     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  1999 Dec 
Date Detail:
Created Date:  1999-12-30     Completed Date:  1999-12-30     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1546-50     Citation Subset:  AIM; IM    
Affiliation:
Department of Anesthesiology and Critical Care Medicine, Tokyo Medical and Dental University, Japan.
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MeSH Terms
Descriptor/Qualifier:
ATP-Binding Cassette Transporters / biosynthesis,  genetics*,  metabolism*
Adult
Amino Acid Transport System X-AG
Animals
Biological Transport
CHO Cells
Cerebral Cortex / enzymology*
Cloning, Molecular
Cold Temperature*
Cricetinae
Glutamic Acid / pharmacokinetics*
Humans
Kinetics
Transfection
Tritium
Chemical
Reg. No./Substance:
0/Amino Acid Transport System X-AG; 10028-17-8/Tritium; 56-86-0/Glutamic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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