Document Detail

The effects of hypertension on the nervous system.
MedLine Citation:
PMID:  2064301     Owner:  NLM     Status:  MEDLINE    
With 60 million Americans meeting criteria for either essential or secondary hypertension, elevated arterial pressures remain a major health problem. While efforts to find etiologies for essential hypertension continue, clinicians battle its effects on organ systems, including the nervous system. Hypertensive changes in the nervous system may be acute, chronic, or both. The intracerebral vasculature is commonly affected. Not infrequently, acute changes including hemorrhage, encephalopathy, and cerebral edema are superimposed on chronic changes of hyaline and fibrinoid arteriolosclerosis. Chronic vascular changes sacrifice vascular lumina. The resulting ischemia is responsible for cystic (lacunar) lesions and subcortical ischemic white matter lesions consistent with Binswanger's disease.
J D Stoner; J C Parker
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of clinical and laboratory science     Volume:  21     ISSN:  0091-7370     ISO Abbreviation:  Ann. Clin. Lab. Sci.     Publication Date:    1991 May-Jun
Date Detail:
Created Date:  1991-08-05     Completed Date:  1991-08-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0410247     Medline TA:  Ann Clin Lab Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  147-52     Citation Subset:  IM    
Department of Pathology, University of Missouri-Truman Medical Center, Kansas City 64108.
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MeSH Terms
Acute Disease
Chronic Disease
Hypertension / complications,  physiopathology*
Nervous System Diseases / etiology,  physiopathology*

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