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The effects of exercise therapy on delirium in cancer patients: a retrospective study.
MedLine Citation:
PMID:  20429015     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
PURPOSE: The present study aimed to investigate the effects of exercise therapy on delirium in cancer patients.
METHODS: We conducted a retrospective study of cancer patients who were admitted to Kyoto University Hospital and referred to the Palliative Care Team. Subjects were divided into two groups [an exercise therapy group (EG) and a non-exercise therapy group (NG)] according to whether exercise therapy was being used for early ambulation at the time delirium occurred. To examine whether any characteristics differed significantly between the two groups, we also compared age, performance status, alcohol use, existence of metastatic brain tumors or preexisting CNS illnesses, levels of opioid exposure, and survival time from the onset of delirium. Moreover, we investigated whether there were differences in antipsychotic drug doses administered between these two groups in order to better analyze the specific effects of exercise therapy on the course of delirium.
RESULTS: EG and NG groups did not differ significantly in terms of any characteristics. The administered dose of antipsychotic drugs was significantly lower in the EG group versus the NG group (2.198 mg versus 5.533 mg, p = 0.036). In comparison, the dose of opioids used did not differ significantly between the two study groups.
CONCLUSIONS: Given the relatively low antipsychotic doses used, it is conceivable that delirium symptoms were attenuated in patients who received exercise therapy. This study suggests that exercise therapy may be useful as one environmental/supportive intervention for delirium.
Authors:
Noriatsu Tatematsu; Akiko Hayashi; Keiichi Narita; Akira Tamaki; Tadao Tsuboyama
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Publication Detail:
Type:  Journal Article     Date:  2010-04-30
Journal Detail:
Title:  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer     Volume:  19     ISSN:  1433-7339     ISO Abbreviation:  Support Care Cancer     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9302957     Medline TA:  Support Care Cancer     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  765-70     Citation Subset:  IM    
Affiliation:
Human Health Science, Graduate School of Medicine, Kyoto University, Shogoin-Kawahara-cho, Sakyo-ku, Kyoto, Japan, 606-8507, noriatsu.t@ay4.ecs.kyoto-u.ac.jp.
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