Document Detail

The effects of an early developmental mother-child intervention program on neurodevelopment outcome in very low birth weight infants: a pilot study.
MedLine Citation:
PMID:  16530990     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Several studies report increased minor neurodevelopment dysfunctions in children born very low birth weight (VLBW). Usefulness of preventive early intervention programs to improve neurodevelopment outcome of VLBW infants is still under investigation. AIMS: To evaluate the effects of an early post-discharge developmental mother-child intervention program on neurodevelopment outcome at 36 months in VLBW infants. STUDY DESIGN: Prospective study. SUBJECTS: 36 VLBW infants ([mean (S.D.)] birthweight=864 g (204 g); gestational age=27.9 weeks (2.4 weeks)), consecutively born January-August 2001, randomized in intervention and control groups. OUTCOME MEASURES: Neurodevelopment assessment at 36 months of chronological age with use of the Griffiths Mental Development Scale and related subscales. RESULTS: At 36 months of chronological age, as compared to controls, children in intervention group exhibited higher scores in personal-social subscales ([mean (S.D.)]=101.4 (9.3) vs. 92.9 (12.1), P=0.02), eye-hand coordination (92.7 (4.5) vs. 87.1 (9.9), P=0.041), practical reasoning (98.6 (8.2) vs. 89.4 (10.1), P=0.01). Development Scale were 97.6 (5.5) and 92.4 (9.9), respectively, in intervention and control groups (P=0.074). CONCLUSIONS: Early post-discharge developmental mother-child intervention program may have a positive effect on later neurodevelopment outcome of VLBW children.
M L Gianní; O Picciolini; M Ravasi; L Gardon; C Vegni; M Fumagalli; F Mosca
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial     Date:  2006-03-13
Journal Detail:
Title:  Early human development     Volume:  82     ISSN:  0378-3782     ISO Abbreviation:  Early Hum. Dev.     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-10-03     Completed Date:  2006-12-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708381     Medline TA:  Early Hum Dev     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  691-5     Citation Subset:  IM    
NICU-Ospedale Maggiore, Cl Mangiagalli-IRCCS-University of Milan, Italy.
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MeSH Terms
Central Nervous System / growth & development*
Child Development / physiology*
Child, Preschool
Early Intervention (Education) / methods*
Infant, Newborn
Infant, Very Low Birth Weight / growth & development*
Intelligence Tests
Learning Disorders / prevention & control
Mother-Child Relations*
Mothers / psychology
Outcome Assessment (Health Care)
Pilot Projects

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