Document Detail

The effects of drugs on psychiatric patients' performance on the Halstead-Reitan neuropsychological test battery.
MedLine Citation:
PMID:  240912     Owner:  NLM     Status:  MEDLINE    
The relationship between the type and amount of psychotropic drug ingestion was evaluated for 184 psychiatric patients using a complex battery of cognitive-sensory-motor tests (Halstead-Reitan). The total patients' group included 68 psychotic patients who were being treated with either phenothiazines or "another drug," and 80 neurotically depressed patients who were taking either no drugs, phenothiazines, minor tranquilizers, tricyclic antidepressants, or sedatives. Little, if any, effect was noted in terms of psychological test performance when individual drug types were combined and considered in terms of dosage. However, upon a more specific analysis of the data, several suggestive trends occurred, demonstrating that individual drugs have variable effects and that some age groupings are more sensitive to drug effects than other groupings. As these trends were a result of a secondary analysis, further investigation was recommended in order to delineate the variables involved. For the present, this investigation has demonstrated the important influence of age and drug type variables upon patient neuropsychological test performance.
M L Howard; T P Hogan; M W Wright
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of nervous and mental disease     Volume:  161     ISSN:  0022-3018     ISO Abbreviation:  J. Nerv. Ment. Dis.     Publication Date:  1975 Sep 
Date Detail:
Created Date:  1975-12-23     Completed Date:  1975-12-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375402     Medline TA:  J Nerv Ment Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  166-71     Citation Subset:  AIM; IM    
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MeSH Terms
Antidepressive Agents, Tricyclic / therapeutic use
Antipsychotic Agents / therapeutic use
Depression / diagnosis,  drug therapy*
Hypnotics and Sedatives / therapeutic use
Monoamine Oxidase Inhibitors / therapeutic use
Psychological Tests*
Psychotic Disorders / diagnosis,  drug therapy*
Psychotropic Drugs / therapeutic use*
Tranquilizing Agents / therapeutic use
Reg. No./Substance:
0/Antidepressive Agents, Tricyclic; 0/Antipsychotic Agents; 0/Hypnotics and Sedatives; 0/Monoamine Oxidase Inhibitors; 0/Phenothiazines; 0/Psychotropic Drugs; 0/Tranquilizing Agents

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