Document Detail


The effects of dietary fibre type on satiety-related hormones and voluntary food intake in dogs.
MedLine Citation:
PMID:  19144213     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Depending on type and inclusion level, dietary fibre may increase and maintain satiety and postpone the onset of hunger. This 7-week study evaluated the effect of fibre fermentability on physiological satiety-related metabolites and voluntary food intake (VFI) in dogs. Sixteen healthy adult dogs were fed a low-fermentable fibre (LFF) diet containing 8.5 % cellulose or a high-fermentable fibre (HFF) diet containing 8.5 % sugarbeet pulp and 2 % inulin. Large intestinal fibre degradation was evaluated by apparent faecal digestibility of nutrients and faecal SCFA and NH3 concentrations. Postprandial blood samples were obtained to determine postprandial plasma glucose, insulin, total peptide tyrosine-tyrosine (PYY), total glucagon-like peptide-1 (GLP-1) and total ghrelin concentrations. At the end of the study, the dogs were given a single meal of a dry dog food to determine VFI. Dogs fed the HFF diet had a significantly higher large intestinal fibre degradation and production of SCFA compared with the dogs fed the LFF diet. The HFF-fed dogs tended (P = 0.058) to show a lower VFI at the end of the study. No treatment effects were found for postprandial plasma glucose, PYY, GLP-1 and ghrelin responses. The concentrations of these metabolites could not be related to the observed difference in VFI. The inclusion of fermentable fibre in canine diets may contribute to the prevention or mitigation of obesity through its effects on satiety. The underlying mechanisms require further investigation.
Authors:
Guido Bosch; Adronie Verbrugghe; Myriam Hesta; Jens J Holst; Antonius F B van der Poel; Geert P J Janssens; Wouter H Hendriks
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2009-01-15
Journal Detail:
Title:  The British journal of nutrition     Volume:  102     ISSN:  1475-2662     ISO Abbreviation:  Br. J. Nutr.     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-07-09     Completed Date:  2009-09-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  318-25     Citation Subset:  IM    
Affiliation:
Animal Nutrition Group, Department of Animal Sciences, Wageningen University, PO Box 338, 6700 AH Wageningen, The Netherlands. guido.bosch@wur.nl
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MeSH Terms
Descriptor/Qualifier:
Ammonia / analysis
Animals
Blood Glucose / analysis
Cellulose
Dietary Fiber / administration & dosage*
Dog Diseases / diet therapy
Dogs / physiology*
Eating*
Fatty Acids, Volatile / analysis
Feces / chemistry
Female
Fermentation
Ghrelin / blood
Glucagon-Like Peptide 1 / blood
Insulin / blood
Inulin
Male
Obesity / diet therapy,  veterinary
Peptide YY / blood
Satiation / physiology*
Vegetables
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Fatty Acids, Volatile; 0/Ghrelin; 106388-42-5/Peptide YY; 11061-68-0/Insulin; 7664-41-7/Ammonia; 89750-14-1/Glucagon-Like Peptide 1; 9004-34-6/Cellulose; 9005-80-5/Inulin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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