Document Detail

The effects of cosmic particle radiation on pocket mice aboard Apollo XVII: appendix III. evaluation of viscera and other tissues.
MedLine Citation:
PMID:  808209     Owner:  NLM     Status:  MEDLINE    
Histopathological findings in the lungs, livers, bone marrows, small intestines, gonads, kidneys, and other tissues of the four pocket mice (Perognathus longimembris) that survived the Apollo XVII flight were evaluated in the light of their immediate environment and as targest of HZE cosmic ray particles. Results of this study failed to disclose changes that could be ascribed to the HZE particle radiation. Decreased numbers of erythropoietic cells in the bone marrow of the flight mice were probably related to the increased oxygen pressure. The small intestine showed no changes. Ovaries and tests appeared normal. Two of the three surviving male flight mice displayed early stages of spermatogenesis, just as ground-based controls did at the same season. Abnormalities were also not found in the thyroid, parathyroids, adrenals, or kidneys. The status of the juxtaglomerular apparatus could not be evaluated. The lungs exhibited nonspecific slight rections. A variety of incidental lesions were noted in the livers of both the flight mice and their controls. The heart muscle showed nothing that could be regarded as pathological. Sections of skeletal muscle examined were free from significant change.
J T Ellis; L M Kraft; C C Lushbaugh; G L Humason; W S Hartroft; E A Porta; O T Bailey; R O Greep; C S Leach; T Laird; R C Simmonds; F S Vogel; R L Dennis; H R Brashear; R V Talmage; G A Harrison; R L Corbett; G Klein; T Tilbury; K Suri; W Haymaker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Aviation, space, and environmental medicine     Volume:  46     ISSN:  0095-6562     ISO Abbreviation:  Aviat Space Environ Med     Publication Date:  1975 Apr 
Date Detail:
Created Date:  1975-11-01     Completed Date:  1975-11-01     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7501714     Medline TA:  Aviat Space Environ Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  639-54     Citation Subset:  IM; S    
Space Flight Mission:
Apollo 17 Project; Flight Experiment; manned; short duration
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MeSH Terms
Adrenal Cortex / radiation effects
Bone Marrow / radiation effects
Cosmic Radiation*
Gonads / radiation effects
Heart / radiation effects
Intestine, Small / radiation effects
Kidney / radiation effects
Liver / radiation effects
Lung / radiation effects
Muscles / radiation effects
Parathyroid Glands / radiation effects
Partial Pressure
Radiation Effects*
Sarcocystosis / epidemiology
Space Flight*
Thyroid Gland / radiation effects
United States
Reg. No./Substance:

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