| The effects on cognitive functions of a movement-based intervention in patients with Alzheimer's type dementia: a pilot study. | |
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MedLine Citation:
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PMID: 20878665 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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OBJECTIVE: To explore the effect of a non-aerobic movement based activity on cognition in people with Alzheimer's type dementia (AD). METHODS: The sample consisted of 27 patients fulfilling the AD ICD-10 diagnostic criteria. The patient sample was randomly divided into two groups: The Exercise Group received 6 weeks movement training and comprised 15 participants with a mean age of 70.5 years (SD: 8). Control Group participated in a standard care group, which served as a control intervention, and consisted of 12 patients with an average age of 75.7 years (SD: 6.90). Cognitive functions were assessed using six computerised tests from the CANTAB, pre and post training. Data were analysed using t-tests. The false discovery rate (FDR) for multiple comparisons as well as Cohen's d effect size was used to assess the significant effects. RESULTS: Significant improvements in sustained attention, visual memory and a trend in working memory were found in the Exercise Group compared to Control Group after the 6 weeks training. In addition, after 6 weeks the Control Group deteriorated significantly in attention, while the AD patients who undertook the physical exercise showed a discrete improvement. CONCLUSIONS: The present study shows that a short course of non-aerobic movement based exercise is already effective at least in some aspects of cognitive functioning in patients with AD. Although the present study is a pilot study with small samples, nevertheless, the results are promising for the further investigation and development of non-aerobic movement programmes. |
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Authors:
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Lidia Yágüez; Kendra N Shaw; Robin Morris; David Matthews |
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Publication Detail:
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Type: Journal Article Date: 2010-09-27 |
Journal Detail:
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Title: International journal of geriatric psychiatry Volume: 26 ISSN: 1099-1166 ISO Abbreviation: Int J Geriatr Psychiatry Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-01-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8710629 Medline TA: Int J Geriatr Psychiatry Country: England |
Other Details:
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Languages: eng Pagination: 173-81 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 John Wiley & Sons, Ltd. |
Affiliation:
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Department of Psychology, King's College London, Institute of Psychiatry, UK. lidia.yaguez@kcl.ac.uk |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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