Document Detail


The effects of closed tracheal suctioning plus volume guarantee on cerebral hemodynamics.
MedLine Citation:
PMID:  21330995     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To compare the effects of open tracheal suctioning (OS) plus intermittent mandatory ventilation (IMV) vs. closed tracheal suctioning (CS) plus volume guarantee ventilation (VG) on changes in mean cerebral blood-flow velocity (CBFv) of ventilated very low birth weight (VLBW) infants.
STUDY DESIGN: A total of 75 normotensive, ventilated VLBW infants (with normal cranial ultrasounds) had monitoring of mean CBFv, PCO2 and mean arterial blood pressure (MABP) before, during and after 220 tracheal suctioning sessions during the first week of life. Multiple linear regression analysis was used to determine the factor(s) influencing the magnitude of relative changes from baseline in mean CBFv after suctioning.
RESULT: In all, 49 VLBW infants receiving IMV had monitoring during 124 OS sessions between July 2002 and May 2005; 26 VLBW infants receiving VG had monitoring during 96 CS sessions between January 2006 and July 2007. The average magnitude of relative changes in mean CBFv was significantly less with CS+VG, and was associated with the magnitude of relative changes in PCO2 and suctioning-ventilator group.
CONCLUSION: The average magnitude of relative changes in mean CBFv was reduced in VLBW infants with CS+VG vs. OS+IMV.
Authors:
J R Kaiser; C H Gauss; D K Williams
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2011-02-17
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  31     ISSN:  1476-5543     ISO Abbreviation:  J Perinatol     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-09-29     Completed Date:  2012-01-25     Revised Date:  2014-09-20    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  671-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Blood Flow Velocity
Blood Pressure
Carbon Dioxide / blood
Cerebrovascular Circulation*
Echoencephalography
Humans
Infant, Newborn
Infant, Very Low Birth Weight*
Intermittent Positive-Pressure Ventilation*
Intubation, Intratracheal*
Respiration, Artificial*
Suction*
Grant Support
ID/Acronym/Agency:
1 K23 NS43185/NS/NINDS NIH HHS; 1 R01 NS060674/NS/NINDS NIH HHS; 1UL1RR029884/RR/NCRR NIH HHS; K23 NS043185/NS/NINDS NIH HHS; K23 NS043185-05/NS/NINDS NIH HHS; R01 NS060674/NS/NINDS NIH HHS; R01 NS060674-05/NS/NINDS NIH HHS; RR20146/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
142M471B3J/Carbon Dioxide
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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